H2 N C O N H2

{Merck Index - © 1952 by Merck & Co., Inc.}

Urea: Carbamide; carbonyldianide. H2NCONH2; mol. wt. 60.06. CH4N2O; C 20.00%, H 6.71%, N 46.65%. Product of protein metabolism. From cyanamide by hydrolyze from CO2 by ammonolysis: Werner, The Chemistry of Urea (London).

Tetragonal prisms. Develops odor of NH3. Cooling, saline taste. m. 132.70. On further heating it decomp. to biuret, NH3, and cyanuric acid. (Ref.) d184 1.32; d184 of water solns. ( w / w ): 10% 1.027; 20% 1.054; 50% 1.145. pH of a 10% water soln. = 7.2. One gram dissolves in 1 ml. water, 10 ml. 95% alcohol, 1 ml. boiling 95% alcohol, 20 ml. abs. alcohol, 6 nil. methanol, 2 ml. glycerol, almost insoluble in chloroform, ether; soluble in concd. HCl. Water solm. decomp. on heating, giving off some NH3.

Use: In Hydroculture, fertilizer, because of easily available high nitrogen content. Is reacted with aldehydes to make resins and plastics. Is condensed with malonic ester to form barbituric acid.

Grades available: Reagent, U.S.P., technical.

Med. Use: Diuretic. Has been used in infected wounds and indolent ulcers.

Contraindications: Impaired renal function. Dose: 0.5 to 8 g.

Vet. Use: As for allantoin. Partial source of dietary nitrogen for ruminants.

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