Energy Deficiency and Cancer

Cancer is a general phenomenon found in the entire spectrum of living organisms, and its derivatives have been found even in viruses. The fact that carcinogenesis relates to particular energy changes in the cell suggests that an energy resource deficiency may be the central carcinogenic mechanism.

This hypothesis offers a new explanation, and suggests methods for the prevention and cure of cancer based on the direct application of high amplitude, plasma-generated pulses of UHF oscillations to cancer cells, and is supported by clinical observations of satisfactory results obtained from this application.

References to the relationship of cell energy level and cancer are found throughout the literature; however, it is believed that this may be the first definition and characterization of cancer cells as cells with low internal energy. We base this on the development of a device that, in supplying electrical energy at a cellular level, has been seen to diminish and even to calcify cancer tumors of nearly all types.

When a cell becomes cancerous, the following facts relating to the internal energy of the cell are observed (Yunis, 1983), (Sheer, 1986), (Dimdi, 1985), (Papaspyrou, 1991):

a.) The number of mitochondria is diminished, thus reducing the activity and energy level of the cell (Deroberts, 1980a).

b.) The ATP–producing function of oxidation-phosphorylation is diminished causing further reduction in available energy (Deroberts, 1980b).

c.) Anaerobic metabolism (glycolysis) increases, acquiring a smaller number of ATP molecules, resulting in limited energy production and reduced thermal energy (Deroberts, 1980b).

d.) The internal level of Na⁺ ions is increased relative to the K⁺ ions, with a twofold result (Apell, 1989), (Nieto-Frausto, 1992), (Schwarz, 1991):

1.) Na⁺ has a large tendency for hydration; one Na⁺ ion can bind at least one H₂O molecule, and water displaces internal thermal energy to the outside (Sturmer, 1991).

2.) High internal Na⁺ concentrations relative to external K⁺ concentration impairs the efficiency of the Na / K pump that exchanges three internal Na⁺ ions with two external K⁺ ions.

Although all four of these phenomena may be interrelated (Szent-Gyorgyi, 1976), they have in common the effect of reducing the internal energy resources of the cancer cell. In case d₍₂₎ above, this is more evident because, according to Goldman's equation (Moore, 1972)., high internal Na⁺ concentration causes a drop in transmembrane potential from a normal healthy cell potential on the order of –50 to –70 mv to a typical cancer cell potential on the order of –15 mf (Cone, 1974, 1985).

A cell with such low transmembrane potential might be compared to a dying battery; according to the Goldman formula (Moore, 1972) the energy level of such a typical cancer cell is less than 5% of that of a normal, healthy cell and thus clearly fits the characterization of the energy resource deficiency hypothesis.